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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TUBA1C
All Species:
41.52
Human Site:
S439
Identified Species:
70.26
UniProt:
Q9BQE3
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BQE3
NP_116093.1
449
49895
S439
Y
E
E
V
G
A
D
S
A
D
G
E
D
E
G
Chimpanzee
Pan troglodytes
Q5R1W4
451
50117
S439
Y
E
E
V
G
V
D
S
V
E
G
E
G
E
E
Rhesus Macaque
Macaca mulatta
XP_001108255
437
48681
M425
F
S
E
A
R
E
D
M
A
A
L
E
K
D
Y
Dog
Lupus familis
XP_850665
449
49891
S439
Y
E
E
V
G
A
D
S
A
E
G
E
D
E
G
Cat
Felis silvestris
Mouse
Mus musculus
P05214
450
49941
S439
Y
E
E
V
G
V
D
S
V
E
A
E
A
E
E
Rat
Rattus norvegicus
Q6AYZ1
449
49919
S439
Y
E
E
V
G
A
D
S
A
E
G
D
D
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510837
454
50448
S442
Y
E
E
V
G
V
D
S
V
E
G
E
G
E
E
Chicken
Gallus gallus
P09644
448
49930
S439
Y
E
E
V
G
L
D
S
Y
E
D
E
E
E
G
Frog
Xenopus laevis
P08537
449
49861
S439
Y
E
E
V
G
A
D
S
A
D
A
E
D
E
G
Zebra Danio
Brachydanio rerio
NP_919369
449
49935
S439
Y
E
E
V
G
A
E
S
V
E
G
E
D
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P06603
450
49890
S439
Y
E
E
V
G
M
D
S
G
D
G
E
G
E
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34690
448
49895
S437
Y
E
E
V
G
A
D
S
N
E
G
G
E
E
E
Sea Urchin
Strong. purpuratus
XP_001178141
451
50085
S439
Y
E
E
V
G
V
D
S
V
E
G
E
G
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P14641
451
49713
F439
Y
E
E
V
G
A
E
F
D
E
G
E
E
G
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.7
96.4
99.3
N.A.
96.2
99.1
N.A.
97.3
94.4
98.8
98.2
N.A.
96.6
N.A.
87.9
96.2
Protein Similarity:
100
98.8
97.3
100
N.A.
98.4
100
N.A.
98.2
96.6
99.7
99.7
N.A.
98.6
N.A.
95.3
98.8
P-Site Identity:
100
66.6
26.6
93.3
N.A.
60
86.6
N.A.
66.6
66.6
93.3
80
N.A.
80
N.A.
66.6
66.6
P-Site Similarity:
100
73.3
40
100
N.A.
66.6
100
N.A.
73.3
80
93.3
93.3
N.A.
80
N.A.
80
73.3
Percent
Protein Identity:
N.A.
84.7
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
94.9
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
50
0
0
36
8
15
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
86
0
8
22
8
8
36
8
8
% D
% Glu:
0
93
100
0
0
8
15
0
0
72
0
86
22
86
36
% E
% Phe:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
93
0
0
0
8
0
72
8
29
8
50
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
0
0
0
0
86
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
93
0
29
0
0
36
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
93
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _